Select Biosciences Ltd

ARTEL and IonGate Join Forces to Advance Drug Discovery Research in North America
IonGate will leverage ARTEL’s expertise to increase the exposure and use of its discovery systems and assay development services in North America.

Trubion Pharmaceuticals Announces Extension of Research Period under its Wyeth Collaboration
Wyeth's obligations to Trubion include collaboration research funding commitments of $3.2 million in exchange for research services through Dec. 22, 2009.

Metabolon Awarded Additional Metabolomics Patent
The newly issued patent further expands the domain of previously issued patents to include multiple disease states related to nervous systems disorders.

Nuevolution Announces Drug Discovery Alliance with Lexicon Pharmaceuticals
Nuevolution's Chemetics® drug discovery technology will be applied to identify small molecule lead compounds against Lexicon drug targets.

Regulatory Services Business Development
Recruiter: VRS Regulatory
Central Scotland, UK

Team Leader, Bioanalysis
Biodynamics Research Limited
Rushden, Northants, UK

Regulatory Toxicologist
VRS Regulatory
Cheshire, UK

Use of Nucleofector® Technology to Establish Stably Expressing Cell Lines
Amaxa GMBH

The number of stably expressing clones resulting from standard transfection experiments is often quite low, especially for cells which are difficult to transfect. This limits many research applications. We show here that the Nucleofector® Technology can successfully be used to generate stably expressing clones at high efficiency. Although a general protocol cannot be given, the data shown here can serve as a guideline for fast establishment of stable transfection protocols for various cell lines

Efficient Delivery of Dharmacon SMARTpool siRNA Reagents in Hard-To-Transfect Cell Lines Using amaxa Nucleofector® 96-well Shuttle® System
Amaxa GMBH

In this Technical Note, Dharmacon and amaxa technologies were applied to Jurkat cells with the aim of performing future siRNA library screens. Jurkat cells are derived from a human acute T-cell leukemia line and are used extensively in the study of T cell signaling and cancer drug development. As with any suspension cell line, Jurkat cells are hard to transfect using reagentmediated delivery.
  

High Throughput Surface Tension Measurement
University of Liverpool, Centre for Materials Discovery

Understanding the surface tension properties of aqueous surfactants and polymer materials is important for the pharmaceutical, coatings, paints, inks, surfactant and household products industries. The traditional methods of measuring surface tension are tedious and time-consuming, so only a few compounds can be measured by a single user per day.

High Throughput Microwave Synthesis of Metal Organic Framework (MOF) Libraries
University of Liverpool, Centre for Materials Discovery

Metal-organic frameworks (MOFs) are an emerging class of new nano-porous materials of considerable academic and industrial interest due to their potential applications in gas storagechiral separations and catalysis. MOFs are prepared from the self-assembly of metal ions (nodes) and organic ligands (spacers), where the structural topology of the resulting crystalline frameworks is driven by the co-ordination preferences of these nodes and spacers. MOFs offer opportunities not available to more cl